Yes. PPSSPP emulator reads both ISO and PBP files. Highly compressed files work perfectly.
For fans of survival horror, the PlayStation Portable (PSP) era was a golden age of terrifying portable action. If you are looking to relive the nightmare without clogging up your storage, you are likely searching for a Resident Evil PSP ISO highly compressed download.
This guide covers which titles are available, the benefits of compressed files, and what you need to know before hitting that download button.
Officially, Sony never released a mainline Resident Evil title exclusively for PSP. However, thanks to emulation and PS1 backward compatibility, you can enjoy the following titles:
No. Resident Evil 4 was never ported to PSP. It was on PS2, GameCube, PC, and later Switch/PS4. Some modders have tried, but no stable ISO exists.