If you are looking at a "YDRP2040" specifically (often a circular or ultra-nano board), the schematic differs slightly from the standard Pico in the following ways:
Look for a 12MHz crystal (Y1) connected to pins XIN (Pin 22) and XOUT (Pin 23). The RP2040’s internal PLL multiplies this to generate the system clock (up to 133MHz). If the YDRP2040 schematic shows a different frequency, it is likely a custom overclocking design. ydrp2040 schematic
The RUN pin (Pin 26) is the global enable for the chip. If you are looking at a "YDRP2040" specifically